Search results for " intestinal morphometry"

showing 2 items of 2 documents

Glucagon-like Peptide-2 and mucosal changes induced by high fat diet in mouse small intestine.

2012

GLP2 receptor expression intestinal morphometry obesity intestinal adaptation.Settore BIO/09 - Fisiologia
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Glucagon-like peptide-2 and mouse intestinal adaptation to a high-fat diet.

2013

Endogenous glucagon-like peptide-2 (GLP2) is a key mediator of refeeding-induced and resection-induced intestinal adaptive growth. This study investigated the potential role of GLP2 in mediating the mucosal responses to a chronic high-fat diet (HFD). In this view, the murine small intestine adaptive response to a HFD was analyzed and a possible involvement of endogenous GLP2 was verified using GLP2 (3–33) as GLP2 receptor (GLP2R) antagonist. In comparison with animals fed a standard diet, mice fed a HFD for 14 weeks exhibited an increase in crypt–villus mean height (duodenum, 27.5±3.0%; jejunum, 36.5±2.9%;P<0.01), in the cell number per villus (duodenum, 28.4±2.2%; jejunum, 32.0±2.9%;P&l…

Malemedicine.medical_specialtyDuodenumEndocrinology Diabetes and MetabolismEndogenyBiologyDiet High-Fatdigestive systemJejunumMiceEndocrinologyInternal medicineIntestine SmallmedicineGlucagon-Like Peptide 2Receptors GlucagonAnimalsMolecular Targeted TherapyObesityIntestinal MucosaReceptorCell ProliferationCell growthdigestive oral and skin physiologyGLP2 receptor expression intestinal morphometry obesity intestinal adaptationGlucagon-like peptide-2Adaptation PhysiologicalSmall intestinePeptide FragmentsUp-RegulationMice Inbred C57BLEndocrinologymedicine.anatomical_structureJejunumKi-67 AntigenDuodenumGlucagon-Like Peptide-2 ReceptorAnti-Obesity AgentsGlucagon-Like Peptide-2 ReceptorSignal TransductionThe Journal of endocrinology
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